Orbach Lab

“The greatest obstacle to discovery is not ignorance -
it is the illusion of knowledge ”

Daniel J. Boorstin

Research

Our lab is fascinated by self-assembly and dynamic behavior of the microtubule cytoskeleton. We are especially interested in the ciliary cytoskeleton, known as the axoneme. Using cutting-edge microscopy techniques, advanced biochemistry, quantitative image analysis and various multidisciplinary approaches we aim to answer basic questions related to the cilia.

Ron gave a talk at the Hebrew University

Ron gave a talk in the Department of Biochemistry and Molecular Biology at the Hebrew University, Faculty of Medicine. A heartfelt thank...

Meet Maria Perlman

We are excited to welcome Maria Perlman to our group as an MSc student. Maria holds a B.Sc. in Life Sciences from Tel-Hai College and she...

Mohammed Passed His Qualifying Exam

Congratulations to Mohammed for successfully passing his qualifying exam! His hard work and dedication have paid off, and now he is ready...

Highlighted Publication

The Dynamic and Structural Properties of Axonemal Tubulins Support the High Length Stability of Cilia

The work describes a novel biochemical assay to purify axonemal tubulins from the central pair and the doublets. Using in vitro work, we characterize two distinct mechanisms that enable tubulins to support the length stability of the axoneme.